Filmed in front of the band's hometown crowd in Seattle over three nights in 2006, the story of Nikki, as originally told on two albums—1988's Operation: Mindcrime and 2006's Operation: Mindcrime II—is the story of one of the most enigmatic characters in the history of Progressive Rock.

Nikki's a junkie, a political revolutionary and an assassin. His relationships with Sister Mary and the manipulative Dr. X form the backbone of a complex tale that is told at the Moore Theater with actors, staging and film.

Three hours long, recorded in DTS-HD Master Audio and Dolby Digital 5.1, with three bonus extras—a tour documentary, a version of "The Chase" from Los Angeles with Ronnie James Dio as Dr. X, and "Queensrÿche Rock'n'Ride" (a documentary on the band's charity motorcycle event)—Mindcrime At The Moore is a high-definition knock-out of a disc that fully presents this mammoth stage production the way it was meant to be told. The band—vocalist Geoff Tate, drummer Scott Rockenfield, bassist Eddie Jackson and guitarists Michael Wilton/Mike Stone—are augmented by Pamela Moore as Sister Mary and the aforementioned Dio who only performed as Dr. X that one time and was shown on film for the rest of the tour.

The 32-song concert ends with an additional two-song encore of fan favorites "Jet City Woman" and "Walk In The Shadows." The two critically acclaimed Mindcrime albums have sold over two million copies in North America alone.